Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,281 – 2,295 of 4,396 results

2,281

Medchemexpress LLC 1-tert-Butyl-3-ethoxybenzene | 133073-81-1 | 95.0% | C12H18O | 250 MG

1-tert-Butyl-3-ethoxybenzene is a drug intermediate used for the synthesis of various active compounds. It is for research use only.

Molecular weight: 178.28
Appearance: Liquid
Color: Light yellow to light brown

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2,282

Medchemexpress LLC LM11A-31 (dihydrochloride) | 1243259-19-9 | 99.9% | 316.27 | 25 MG

LM11A-31 dihydrochloride is a non-peptide p75NTR (neurotrophin receptor p75) modulator and an orally active, potent proNGF (nerve growth factor) antagonist. It is an amino acid derivative that readily crosses the blood-brain barrier and inhibits p75-mediated cell death. This compound has been shown to reverse cholinergic neurite dystrophy in mouse models of Alzheimer's disease during mid- to late-stage disease progression. It is intended for research use only and is not sold to patients.

Non-peptide p75NTR modulator
Orally active and potent proNGF antagonist
Amino acid derivative with high blood-brain barrier permeability
Blocks p75-mediated cell death
Reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models
Mitigates proNGF accumulation and preserves BRB integrity in animal models

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2,283

TARGETMOL CHEMICALS INC MAK-683 HYDROCHLORIDE 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg and bulk. Please contact Fisher for quotes. MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED) (patent US20160176882 A1 compound example 2). MAK683 exhibits IC50s of 59 26 89 nM in EED Alphascreen binding ELISA and LC-MS assay. purity: 98%

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2,284

eMolecules 1227608-04-9 | 7-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | MFCD16659699 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc2cccnc2cc1O | 0.1g | 798867649

7-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | 1227608-04-9 | MFCD16659699 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc2cccnc2cc1O | 0.1g | 798867649

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2,285

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML

AL-611 is an HCV NS5B polymerase inhibitor with an EC50 of 5 nM, intended for research use only.

Molecular weight of 614.54.
Purity of 99.93%.
Appears as a solid, white to off-white.
Soluble in DMSO (125 mg/mL).
Store powder at -20°C for up to 3 years.
Store in solvent at -80°C for 6 months, or -20°C for 1 month.
Exhibits CC50 > 100 μM and EC50 0.005 μM in Huh-7 cells.
Involved in a Phase 1 clinical trial for Hepatitis C (NCT03253471).

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2,286

TARGETMOL CHEMICALS INC MURAGLITAZAR 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Muraglitazar (BMS-298585) is a PPAR (alpha)/(gamma) dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPAR(alpha) and PPAR(gamma) with EC50 of 320 nM and 110 nM respectively. purity: 99%

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2,287

Medchemexpress LLC Mal-amido-(CH2COOH)2 | 207613-14-7 | 99.2% | 284.22 g/mol | C11H12N2O7

Mal-amido-(CH2COOH)2 compound 7a is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1]

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2,288

Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 10 MG

Pyrroloquinoline quinone disodium salt is a water-soluble redox cofactor used as a research reagent in studies of cellular metabolism, mitochondrial function, and oxidative stress. The disodium salt form enhances solubility for aqueous assays and small-scale formulations, and is typically supplied with high purity for experimental reproducibility.

Water-soluble form suitable for aqueous assays.
Acts as a redox cofactor for metabolism and mitochondrial studies.
High purity supports reproducible experimental results.
Appropriate for biochemical and cell biology applications.
Available in small quantities for screening and pilot studies.

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2,289

eMolecules 4925-88-6 | 2,5-Dimethoxy-4-methylbenzaldehyde | ChemScene | MFCD02253192 | 180.203 | C10H12O3 | 98.000 | COc1cc(C=O)c(OC)cc1C | 5g | 632290994

2,5-Dimethoxy-4-methylbenzaldehyde | ChemScene | 4925-88-6 | MFCD02253192 | 180.203 | C10H12O3 | 98.000 | COc1cc(C=O)c(OC)cc1C | 5g | 632290994

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2,290

Medchemexpress LLC 1,4,7-trimethyl-1,4,7-triazacyclononane | 96556-05-7 | MFCD00006093 | 98.5% | 171.28 g/mol | C9H21N3 | 5 G

1,4,7-trimethyl-1,4,7-triazacyclononane is a small cyclic tertiary amine used as a reagent in biochemical assays and as a crosslinking or reactive reagent for research applications.

used as a reagent in biochemical assays
serves as a crosslinking or reactive reagent in research
molecular formula c9h21n3
molecular weight 171.28 g/mol
high purity, typically about 98.5%

Pricing & Availability

2,291

Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | MFCD00274123 | 98.0% | 560.59 g/mol | C31H32N2O8 | 10 G

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a DMT-protected 2'-O-methyl uridine nucleoside used as a building block and intermediate for solid-phase oligonucleotide synthesis and for research on modified RNA. It is supplied as a high-purity solid or as a DMSO solution to facilitate incorporation into synthesis workflows.

DMT-protected 2'-O-methyl uridine suitable for oligonucleotide synthesis.
High purity (98.03%) for reliable reactions.
Available as powder and 10 mM solution in DMSO for flexibility.
Long-term storage stability when kept at recommended temperatures.
Datasheet, COA, and SDS available to support quality control.

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2,292

TARGETMOL CHEMICALS INC AP 18 5MG

Also available in 1mg 2mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1 respectively. AP-18 could reverse complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 could attenuate Yo-Pro uptake induced by 30 μM AITC in a concentration-dependent manner (IC50= 10.3 μM). purity: 99%

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2,293

Medchemexpress LLC Mal-amido-PEG9-acid | 2112731-43-6 | 99.5% | 250 MG

Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. These PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and has not been fully validated for medical applications.

PEG-based linker
Used in synthesis of PROTACs
Facilitates selective degradation of target proteins
Utilizes ubiquitin-proteasome system
Contains two ligands connected by a linker

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2,294

TARGETMOL CHEMICALS INC LOC14 25MG

Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. LOC14 to be the most potent PDI inhibitor reported to date( EC50 500 nM)purity: 98%

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2,295

Medchemexpress LLC 1-cyclobutyl-3-(2,6-dimethylphenyl)-7-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropy | 2172617-15-9 | 99.8% | 50MG

1-cyclobutyl-3-(2,6-dimethylphenyl)-7-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropy | 2172617-15-9 | 99.8% | 50MG

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Quinolines and derivatives

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Medchemexpress LLC 1-tert-Butyl-3-ethoxybenzene | 133073-81-1 | 95.0% | C12H18O | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LM11A-31 (dihydrochloride) | 1243259-19-9 | 99.9% | 316.27 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC MAK-683 HYDROCHLORIDE 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC MURAGLITAZAR 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mal-amido-(CH2COOH)2 | 207613-14-7 | 99.2% | 284.22 g/mol | C11H12N2O7 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1,4,7-trimethyl-1,4,7-triazacyclononane | 96556-05-7 | MFCD00006093 | 98.5% | 171.28 g/mol | C9H21N3 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | MFCD00274123 | 98.0% | 560.59 g/mol | C31H32N2O8 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC AP 18 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mal-amido-PEG9-acid | 2112731-43-6 | 99.5% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC LOC14 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-cyclobutyl-3-(2,6-dimethylphenyl)-7-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropy | 2172617-15-9 | 99.8% | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More